Combined Upper Blepharoplasty with Plasmage Exeresis: A Synergistic Approach to Periorbital Rejuvenation

Purpose: The aging process affects skin in the periorbital and upper eyelid areas, leading to wrinkling, thinning, and drooping. Upper blepharoplasty is a commonly performed surgical procedure, but optimal excision technique remains debated. This study’s goal is to evaluate the effectiveness and safety of plasmage exeresis as a supplementary procedure following upper blepharoplasty.
Methods: In this observational study, 50 patients with moderate upper blepharochalasis were enrolled to recieve plasmage exeresis technology (Plexr® device) as treatment following upper blepharoplasty, the study was conducted at Alexandria University Hospital, Egypt from the period from 1st of January 2021 to 30th of January 2022. 
Results: The study includes 50 patients aged 15 to 57 years (median 34 years), with a significant male-female ratio (34% male, 66% female) (p < 0.023*). Pre-treatment margin-crease distance ranged from 0.5 to 3 mm (median 1 mm), with no significant difference (p >0.252). Complications were minimal, predominantly eye swelling (100%), while satisfaction evaluation at 6, 8, and 12 months showed significant improvements in pre margin-crease distance (p < 0.0001*), underscoring Plexr®'s lasting efficacy for upper eyelid rejuvenation. 
Conclusions: Plasmage exeresis as a supplementary procedure following upper blepharoplasty demonstrates favorable efficacy and safety outcomes. The study findings highlight minimal complications, predominantly eye swelling, and significant improvements in pre margin-crease distance, indicating the lasting efficacy of Plexr® for upper eyelid rejuvenation. This combined approach holds promise as an effectivetreatment option for upper blepharochalasis.